Experiment 522204

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

WORTMANNIN

Details

PropertyValue
Pharmacology
PROTEIN BINDING
OrganismEmpty organism
CitationTHELEN,M: WYMANN,MP: LANGEN,H:. (1994). WORTMANNIN BINDS SPECIFICALLY TO 1-PHOSPHATIDYLINOSITOL 3-KINASE WHILE INHIBITING GUANINE NUCLEOTIDE-BINDING PROTEIN-COUPLED RECEPTOR SIGNALING IN NEUTROPHIL LEUKOCYTES.. 91(11)
Amount utilized
Compound isolated
DiseaseBINDS TO WARTMANNIN BINDING SITES ON NEUTROPHILS.
Dose amount5.0 NANOMOLS
Number2
Qualitative resultACTIVE
Dose expressionIC50