Experiment 523044

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

CANTHAXANTHIN

Details

PropertyValue
Pharmacology
CELL DIFFERENTIATION INDUCTION
OrganismEmpty organism
CitationNIKAWA,T: SCHULZ,WA: VAN DEN BRINK,CE: HANUSCH,M: VAN DER SAAG,P: STAHL,W: SIES,H:. (1995). EFFICACY OF ALL-TRANS-BETA-CAROTENE, CANTHAXANTHIN, AND ALL-TRANS-, 9-CIS, AND 4-OXORETINOIC ACIDS IN INDUCING DIFFERENTIATION OF AN F9 EMBRYONAL CARCINOMA RARBETA-LACZ REPORTER CELL LINE.. 316(2)
Amount utilized
Compound isolated
DiseaseRAR-BETA-2-PROMOTER COUPLED TO LAC7 REPORTER GENE. EFFECT PROBABLY DUE TO BREAKDOWN OF THE COMPOUND TO RETINOIC ACID, WHICH IS A POWERFUL INDUCER.
Dose amount10.0 MICROMOLS
Number1
Qualitative resultWEAK ACTIVITY
AnimalCELL CULTURE
Dose expressionCONC USED