Experiment 525516
Worktypes
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | INTRAGASTRIC |
| Organism | Withania somnifera (SOLANACEAE) |
| Citation | BHATTACHARYA,SK: KUMAR,A: GHOSAL,S:. (1995). EFFECTS OF GLYCOWITHANOLIDES FROM WITHANIA SOMNIFERA ON AN ANIMAL MODEL OF ALZHEIMER'S DISEASE AND PERTURBED CENTRAL CHOLINERGIC MARKERS OF COGNITION IN RATS.. 9(2) |
| Amount utilized | |
| Compound isolated | |
| Disease | VS.IBOTENIC ACID-INDUCED LESIONING OF NUCLEUS BASALIS MAGNOCELLULAPIS, DECREASED FRONTAL CORTICAL AND HIPPOCAMPAL ACETYLCHOLINE LEVELS, CHOLINE ACETYL TRANSFERASE ACTIVITY AND MUSCARINIC CHOLINERGIC RECEPTOR BINDING, AS WELL AS ATTENUATION OF LEARNED ACTIVE AVOIDANCE. |
| Dose amount | 50.0 MG |
| Number | 1 |
| Qualitative result | ACTIVE |
| Animal | RAT |
| Per unit | KG |
| Dose expression | DOSE |
| Extract | H2O EXT |