Experiment 525577

Worktypes

PHARMACOLOGY OF COMPOUND - IN HUMANS

Compounds isolated

ROOPEROL,DEHYDROXY:ROOPEROLROOPEROL,BIS-DEHYDROXY:HYPOXOSIDEHYPOXOSIDE,DEHYDROXY:HYPOXOSIDE,BIS-DEHYDROXY:

Details

PropertyValue
Pharmacology
METABOLISM OF
Administration routeORAL
OrganismHypoxis latifolia (HYPOXIDACEAE)
CitationKRUGER,PB: ALBRECHT,CFDV: LIEBENGERG,RW: VAN JAARSVELD,PP:. (1994). STUDIES ON HYPOXOSIDE AND ROOPEROL ANALOGUES FROM HYPOXIS ROOPERI AND HYPOXIS LATIFOLIA AND THEIR BIOTRANSFORMATION IN MAN BY USING HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY WITH IN-LINE SORPTION ENRICHMENT AND DIODE-ARRAY DETECTION.. 662(1)
Amount utilized
Compound isolated
DiseaseROOPEROL, AGLUCONE OF GIVEN COMPOUND, WAS METABOLIZED TO A DEHYDROXY AND BIS-DEHYDROXY ADDUCTS. AND ALL 3 COMPOUNDS OCCURRED AS DIGLUCURIDES, DISULFATE OR GLUCURONIDE-SULFATE CONJUGATES IN SERUM. NO ROOPEROL OR GIVEN COMPOUND OCCURRED IN SERUM.
Dose amount1.0 GM
Number2
Qualitative result.
AnimalHUMAN ADULT
Per unitPERSON
Dose expressionDOSE