Experiment 530549

Worktypes

ANTICANCER AND/OR CYTOTOXICITY MARKER CODEPHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

HARRINGTONINE

Alerts

DATA INCOMPLETE - DERIVED FROM AN ABSTRACT.

Details

PropertyValue
Pharmacology
CYTOTOXIC ACTIVITY
OrganismEmpty organism
CitationYAMAMOTO S: HUI,PZ: FUKUDA,Y: TATSUMI,K: MINO,M:. (1989). POTENTIATION OF HARRINGTONINE CYTOTOXICITY BY CALCIUM ANTEGONIST DILTIAZEM AND BISCOCLAURINE ALKALOID CEPHARANTHINE IN ADRIAMYCIN-RESISTANT P388 MURINE LEUKEMIA AND K562 HUMAN LEUKEMIA CELLS.. 18(6)
Amount utilized
Compound isolated
DiseaseACTIVITY IS ENHANCED BY CALCIUM INFLUX BLOCKERS (LIKE DILTIAZEM) 9-10 FOLD, IN CELL LINES WERE IT SHOWED CROSS RESISTANCE WITH ADRIAMYCIN.
Number1
Qualitative resultACTIVE
AnimalCELL CULTURE
Dose expressionCONC USED