Experiment 53242
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | IM |
| Organism | Ligusticum wallichii (APIACEAE) |
| Citation | CHUN-SHENG,L: HSIAO-MENG,Y: YIN-HSIANG,H: CHUN,P- CII-FEN,S:. (1978). RADIX SALVIAE MILTIORRHIZAE AND RHIZOMA LIGUSTICI WALLICHII IN CORONARY HEART DISEASE.. 4(1) |
| Amount utilized | |
| Compound isolated | |
| Disease | A MIXTURE OF LIGUSTICUM WALLICHII AND SALVIA MILTIORRHIZA WAS USED. IN THIS STUDY 105 PATIENTS WITH VARYING DEGREES OF ANGINA PECTORIS WERE TREATED THE EXTRACT WAS GIVEN ONCE OR TWICE A DAY FOR 60 DAYS OR MORE,56 RECEIVED TREATMENT FOR 6 MONTHS. THERE WAS A RELATIONSHIP BETWEEN THERAPEUTIC EFFECT AND SEVERITY OF DISEASE. THE TREATMENT WAS EFFECTIVE IN 39 CASES (37.1%) 20 MILD,17 MODERATE AND 2 SEVERE CASES OF ANGINA PECTORIS. THE TREATMENT BROUGHT RELIEF IN 61 CASES,33 OF WHICH WERE MILD AND 28 OF WHICH WERE MODERATE. THERAPEUTIC EFFECTS WERE SEEN 1 TO 4 WEEKS AFTER INITIATING INJECTIONS. NO OBVIOUS CHANGES WERE SEEN IN BLOOD PRESSURE OR HEART RATE. IMPROVEMENT OF ELECTROCARDIOGRAMS WERE SEEN IN SEVERAL PATIENTS. THE ONLY SIDE EFFECT NOTED WAS THE APPEARANCE OF SKIN ERRUPTIONS ON THE LIMBS OF ONE PATIENT WHICH DISSAPEARED AFTER TREATMENT WAS STOPPED. |
| Dose amount | 4.0 GM |
| Number | 1 |
| Qualitative result | ACTIVE |
| Animal | HUMAN ADULT |
| Dose expression | DOSE |
| Extract | HOT H2O EXT |