Experiment 535768

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVO

Compounds isolated

PUROMYCIN

Alerts

VS.HOT PLATE METHOD.REPORTED BIOLOGICAL ACTIVITY IS HIGHLY DOSE-DEPENDENT.DATA INCOMPLETE - DERIVED FROM AN ABSTRACT.

Details

PropertyValue
Pharmacology
ANALGESIC ACTIVITY
Administration routeICV
OrganismEmpty organism
CitationHERMAN,ZS: STACHURA,Z: LASKAWIEC,G: KOWALSKI,J: OBUCHOWICZ,E:. (1985). ANTINOCICEPTIVE EFFECTS OF PUROMYCIN AND BACITRACIN.. 37(2)
Amount utilized
Compound isolated
DiseaseACTIVITY WAS ABOLISHED BY NALOXONE, AND IT IS DUE TO AN INCREASE OF ENKEPHALINS BY INHIBITION OF AMINOPEPTIDASE.
Dose amount100.0 MCG
Number1
Qualitative resultACTIVE
AnimalRAT
Dose expressionDOSE