Experiment 536834

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVO

Compounds isolated

ACONITINE

Details

PropertyValue
Pharmacology
CHRONOTROPIC EFFECT NEGATIVE
Administration routeIP
OrganismEmpty organism
CitationKIMURA,I: MAKINO,M: MATSUI,T: TAKADA,M: KIMURA,M:. (1994). ACONITINE-INDUCED BRADYCARDIA, CENTRALLY ACTING MUSCARINIC EFFECTS ARE INHIBITED PERIPHERALLY BY HIGENAMINE IN CONSCIOUS MICE.. 8(3)
Amount utilized
Compound isolated
DiseaseINHIBITED BY HIGENAMINE, SCOPOLAMINE BUT NOT PROTOPINE. ALSO INHIBITED BY HEXAMETHONIUM MECAMYLAMINE.
Dose amount30.0 MCG
Number2
Qualitative resultACTIVE
AnimalMOUSE
Per unitKG
Dose expressionDOSE
GenderMALE