Experiment 549843
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Organism | Empty organism |
| Citation | CRITCHFIELD,JW: WELSH,CJ: PHANG,JM: YEH,GC:. (1994). MODULATION OF ADRIAMYCIN ACCUMULATION AND EFFLUX BY FLAVONOIDS IN HCT-15 COLON CELLS. ACTIVATION OF P-GLYCOPROTEIN AS A PUTATIVE MECHANISM.. 48(7) |
| Amount utilized | |
| Compound isolated | |
| Disease | DECREASED ADRIAMYCIN ACCUMULATION IN P-GLYCOPROTEIN EXPRESSING CELLS. EFFECT INHIBITED BY MULTI-DRUG RESISTANCE REVERSAL AGENTS VERAPAMIL, VINBLASTINE AND QUINIDINE. |
| Dose amount | 100.0 MICROMOLS |
| Number | 21 |
| Qualitative result | ACTIVE |
| Animal | CELL CULTURE |
| Dose expression | CONC USED |