Experiment 552877

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

IBOGAINE

Details

PropertyValue
Pharmacology
N-METHYL-D-ASPARTATE MODULATORY ACTIVITY
OrganismEmpty organism
CitationMASH,DC: STALEY,JK: PABLO,JP: HOLOHEAN,AM: HACKMAN,JC: DAVIDOFF,RA:. (1995). PROPERTIES OF IBOGAINE AND ITS PRINCIPAL METABOLITE (12-HYDROXYIBOGAMINE) AT THE MK-801 BINDING SITE OF THE NMDA RECEPTOR COMPLEX.. 192(1)
Amount utilized
Compound isolated
DiseaseCOMPETITIVELY DISPLACES MK-801 FROM NMDA RECEPTOR AND INHIBITS NMDA-INDUCED DEPOLARIZATION.
Dose amount100.0 MICROMOLS
Number1
Qualitative resultACTIVE
AnimalFROG
Dose expressionCONC USED