Experiment 552878

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

IBOGAINE,12-HYDROXY:

Details

PropertyValue
Pharmacology
N-METHYL-D-ASPARTATE MODULATORY ACTIVITY
OrganismEmpty organism
CitationMASH,DC: STALEY,JK: PABLO,JP: HOLOHEAN,AM: HACKMAN,JC: DAVIDOFF,RA:. (1995). PROPERTIES OF IBOGAINE AND ITS PRINCIPAL METABOLITE (12-HYDROXYIBOGAMINE) AT THE MK-801 BINDING SITE OF THE NMDA RECEPTOR COMPLEX.. 192(1)
Amount utilized
Compound isolated
DiseaseCOMPETITIVELY DISPLACES MK-801 FROM NMDA RECEPTOR AND INHIBITS NMDA-INDUCED DEPOLARIZATION.
Dose amount1.0 MILLIMOLS
Number2
Qualitative resultACTIVE
AnimalHUMAN ADULT
Dose expressionCONC USED