Experiment 560115

Worktypes

ANTICANCER AND/OR CYTOTOXICITY MARKER CODEPHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

OLEANOLIC ACID-3-O-ALPHA-L-ARABINOPYRANOSIDEHEDERAGENIN-3-O-(BETA-D-GLUCOPYRANOSYL(1-4)-ALPHA-L-ARABINOPYRANOSIDE)TAUROSIDE B

Details

PropertyValue
Pharmacology
CYTOTOXIC ACTIVITY
OrganismFatsia japonica (ARALIACEAE)
CitationKITANAKA,S: YASUDA,I: KASHIWADA,Y: HU,CQ: BASTOW,KF: BORI,ID: LEE,KH:. (1995). ANTITUMOR AGENTS, 162. CELL-BASED ASSAYS FOR IDENTIFYING NOVEL DNA TOPOISOMERASE INHIBITORS: STUDIES ON THE CONSTITUENTS OF FATSIA JAPONICA.. 58(11)
Amount utilized
Compound isolated
DiseaseCOMPOUND APPEARS TO INTERFERE WITH VP-16- UPTAKE, THERABY INHIBITING CLEAVABLE COMPLEX FORMATION, NOT BY FUNCTIONING AS TOPOISOMERASE ILINHIBITOR.
Dose amount2.5 MCG
Number3
Qualitative resultACTIVE
AnimalCELL CULTURE
Per unitML
Dose expressionIC50