Experiment 561076
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | SC |
| Organism | Empty organism |
| Citation | MAYWOOD,ES: BITTMAN,EL: HASTINGS,MH:. (1996). LESIONS OF THE MELATONIN- AND ANDROGEN-RESPONSIVE TISSUE OF THE DORSOMEDIAL NUCLEUS OF THE HYPOTHALAMUS BLOCK THE GONADAL RESPONSE OF MALE SYRIAN HAMSTERS TO PROGRAMMED INFUSIONS OF MELATONIN.. 54() |
| Amount utilized | |
| Compound isolated | |
| Disease | CMPD BOUND IN DORSOMEDIAL NUCLESU OF HYPOTHALAMUS. CMPD CAUSES GONADALATROPHY AND DECREASED LEUTHENIZING HORMONE(MU) AND PROLACTIN LEVELS. LESIONING OF DORSOMEDIAL NUCLEUS PREVENTED ATROPHY AND DECREAS LH LEVEL IN PINEALECTOMIZED ANIMALS. |
| Dose amount | 500.0 NG |
| Number | 1 |
| Qualitative result | ACTIVE |
| Animal | HAMSTER(SYRIAN) |
| Per unit | ANIMAL |
| Dose expression | DOSE |