Experiment 565627

Worktypes

PATENT DESCRIBEDANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

CUNANIOL,TRANS:

Alerts

BIOLOGICAL ACTIVITY REPORTED HAS BEEN PATENTED.DATA INCOMPLETE - DERIVED FROM AN ABSTRACT.

Details

PropertyValue
Pharmacology
ANTIMYCOBACTERIAL ACTIVITY
OrganismClibadium sylvestre (ASTERACEAE)
CitationGORINSKY,C:. (1994). POLYACETYLENES FROM CLIBADIUM SYLVESTRE AND THEIR USES.. ()
Amount utilized
Compound isolated
DiseaseTRANS-CUNANOIL AND ITS CIS ISOMER ARE EXTRACTED FROM LEAVES OF C. SYLVESTRE WITH MEOH-PETROLEUM ETHER-WATER AND SEPARATED BY COUNTERCURRENT DISTRIBUTION. AC AND GLUCOSYL DERIVATIVES (R ALKYL, ACYL, GLYCOSYL) AND THEIR ANHYDRO AND KETO ANALOGS ARE PROPOSED FOR USE IN THERAPY, ESPECIALLY AS REVERSIBLE HEART-BLOCKING, NEUROMUSCULAR, ON NEUROACTIVE AGENTS OR FOR USE AS PESTICIDES OR MYCOBACTERICIDES.
Number2
Qualitative resultACTIVE
AnimalAGAR PLATE
Dose expressionCONC USED