Experiment 565637

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVOPATENT DESCRIBED

Compounds isolated

GLYCYRRHETINIC ACID

Alerts

BIOLOGICAL ACTIVITY REPORTED HAS BEEN PATENTED.A MIXTURE OF PURE COMPOUNDS WAS USED TO OBTAIN THE REPORTED EFFECT.DATA INCOMPLETE - DERIVED FROM AN ABSTRACT.

Details

PropertyValue
Pharmacology
SKIN DEPIGMENTATION EFFECT
Administration routeEXTERNAL
OrganismEmpty organism
CitationNISHIZAWA,Y: KITAYAMA,T: KIMURA,M: YADA,Y: IMOKAWA,G:. (1994). SKIN-LIGHTENING COSMETICS CONTAINING GLYCYRRHETINIC ACID AND ASCORBIC ACID PHOSPHATE.. ()
Amount utilized
Compound isolated
DiseaseSKIN-LIGHTENING COSMETICS CONTAIN GLYCYRRHETINIC ACID (I) AND/OR ITS ESTERS AND ASCORBIC ACID PHOSPHATE (II) AND/OR ITS SALTS. A SOLN. CONTG. I AND II MG SALT (III) SHOWED MARKED SKIN-LIGHTENING EFFECT ON THE UV-INDUCED PIGMENTATION IN BROWN GUINEA PIGS. I 2.0, III 3.0, GLYCERIN 4.0, POLYOXYETHYLENE HYDROGENATED CASTOR OIL 1.5 ETOH 10.0, NA PYRROLIDONECARBOXYLATE 2.0 WT %, PERFUME, AND H2O BALANCE WERE MIXED TO GIVE A LOTION.
Dose amount1.0%
Number1
Qualitative resultACTIVE
AnimalGUINEA PIG
Dose expressionCONC USED