Experiment 566392

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVO

Compounds isolated

SPERGUALIN,15-DEOXY:CYCLOSPORIN A

Details

PropertyValue
Pharmacology
DIABETES-INHIBITION OF DEVELOPMENT
Administration routeIP
OrganismEmpty organism
CitationHABERSTROH,J: WILHELM,T: SCHULTE-MONTING,J: SCHORLEMMER,HU: VON SPECHT,BU:. (1995). PREVENTION OF TYPE I DIABETES IN THE NON-OBESE DIABETIC (NOD) MOUSE WITH 15-DEOXYSPERGUALIN (15-DS) OR 15-DS + CYCLOSPORIN A (CYA).. 48(2)
Amount utilized
Compound isolated
DiseaseASSAYED IN ANIMALS BRED FOR ALMOST 100% INCIDENCE OF INSULIN-DEPENDENT DIABETES. TREATMENT DECREASED INCIDENCE TO 47%. COADMINISTRATION OF CYCLOSPORINE A DID NOT ENHANCE THE EFFECT.
Dose amount2.0 MG
Number1
Qualitative resultACTIVE
AnimalMOUSE
Per unitKG
Dose expressionDOSE