Experiment 568678
Worktypes
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Organism | Empty organism |
| Citation | CHEN,CX: JIN,RM: WANG,Q: ZHANG,HG:. (1995). EFFECTS OF RHYNCHOPHYLLINE ON GUINEA PIG ATRIA.. 4(3) |
| Amount utilized | |
| Compound isolated | |
| Disease | THE AUTHORS STUDIED THE EFFECTS OF RHYNCHOPHYLLINE ON SOME ELECTROPHYSIOL. CHARACTERS IN ISOLATED GUINEA PIG ATRIS. RHYNCHOPHYLLINE DECREASED THE BEATING RATE IN SPONTANEOUSLY BEATING RIGHT ATRIA. IN LEFT STRIA DRIVEN BY ELEC., RHYNCHOPHYLLINE PRODUCED A NEG. ACTION. THE RESULTS SHOWED THAT RHYNCHOPHYLLINE SUPPRESSED THE AUTOMATICITY EVOKED BY EPINEPHRINE, PROLONGED THE FRP AND INHIBITED THE EXCITABILITY IN ISOLATED GUINEA PIG ATRIA. RHYNCHOPHYLLINE ALSO INHIBITED THE POS. STAIRCASE PHENOMENON. THE RESULTS ARE RELATED TO THE ANTIARRHYTHMIC ACTIVITY OF RHYNCHOPHYLLINE. |
| Number | 1 |
| Qualitative result | ACTIVE |
| Animal | GUINEA PIG |
| Dose expression | CONC USED |