Experiment 574013

Worktypes

STRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEPHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

TRICHOSANTHIN,ALPHA:

Details

PropertyValue
Pharmacology
EMBRYOTOXIC EFFECT(RELATED TO GENERAL TOXIC EFFECTS)
OrganismEmpty organism
CitationCHAN,WY: NG,TB: SHAW,PC:. (1995). MOUSE EMBRYONIC DEVELOPMENT AND TUMOR CELL GROWTH UNDER THE INFLUENCE OF RECOMBINANT TRICHOSANTHIN (A RIBOSOME INACTIVATING PROTEIN) AND ITS MUTEINS.. 15(5)
Amount utilized
Compound isolated
DiseaseWHOLE EMBRYO CULTURE TECHNIQUE USED. RECOMBINANT MUTATED FORMS OF CMPD ASSAYED AS WELL. TWISTED BODY AXIS, ABSENCE OF LIMB BUDS AND ABNORMAL BRANCHIAL APPARATUS NOTED.
Dose amount50.0 MICROMOLS
Number1
Qualitative resultACTIVE
AnimalMOUSE
Dose expressionCONC USED