Experiment 579162

Worktypes

EFFECTS DUE TO A COMBINATION OF DRUGSPHARMACOLOGY OF EXTRACT - IN VIVO

Alerts

EFFECTS DESCRIBED ARE FROM A MULTI-COMPONENT RX.DATA INCOMPLETE - DERIVED FROM AN ABSTRACT.

Details

PropertyValue
Pharmacology
TOXIC EFFECT(GENERAL)
Administration routeINTRAGASTRIC
OrganismRosa species (ROSACEAE)
CitationUBASHEEV,IO: LONSHAKOVA,KS: MATKHANOV,EI: AZHUNOVA,TA: TOLMACHEVA,EL: STRUBINOVA,VN:. (1988). CELLULAR-MOLECULAR ASSESSMENT OF TOXICITY AND EMBRYOTOXICITY OF CHOLAGOGIC HERBAL TEA.. 22(4)
Amount utilized
Compound isolated
DiseaseTHE CHRONIC TOXICITY, EMBRYOTOXICITY, AND TERATOGENICITY OF A CHOLAGOGIC HERBAL TEA (MIXT. OF HELICHRYSUM ARENARIUM, TANACETUM VULGARE, MENTHA PIPERITA, URTICA DIOICA, GLYCYRRHIZA GLABRA, AND ROSA) WERE STUDIED IN RATS AND DOGS. THE TEA HAD NO ADVERSE EFFECTS ON INTERNAL ORGANS, RAT EMBRYOS AND FETUSES, AND POSTNATAL DEVELOPMENT. IT HAD A STABILIZING EFFECT ON THE LIVER IN ANIMALS POISONED WITH CCL4 AND ACTIVATED MICROSOMAL MONOOXYGENASES.
Number1
Qualitative resultINACTIVE
AnimalRAT
Dose expressionDOSE
ExtractINFUSION