Experiment 59486

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODESTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE

Compounds isolated

EMETINE,(-):

Alerts

DOSING ON DAY 1 ONLY.

Details

PropertyValue
Pharmacology
ANTITUMOR ACTIVITY
Administration routeIP
OrganismEmpty organism
CitationJONDORF,WR: ABBOTT,BJ: GREENBERG,NH: MEAD,JAR:. (1971). INCREASED LIFESPAN OF LEUKEMIC MICE TREATED WITH DRUGS RELATED TO (-)EMETINE.. 16()
Amount utilized
Compound isolated
DiseaseDOSE RANGE WAS FROM 8-128 MG PER KILOGRAM. DOSE WAS GIVEN EVERY 3 HOURS. EMETINE DIHYDRICHLORIDE WAS USED.
Dose amountVAR
Number4
Percent yield43%
Qualitative resultACTIVE
AnimalMOUSE
Dose expressionDOSE
Expression resultILS