Experiment 59489

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODESTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE

Compounds isolated

EMETINE,(-):

Details

PropertyValue
Pharmacology
ANTITUMOR ACTIVITY
Administration routeIP
OrganismEmpty organism
CitationJONDORF,WR: ABBOTT,BJ: GREENBERG,NH: MEAD,JAR:. (1971). INCREASED LIFESPAN OF LEUKEMIC MICE TREATED WITH DRUGS RELATED TO (-)EMETINE.. 16()
Amount utilized
Compound isolated
DiseaseDOSE WAS GIVEN ON DAY 1 AND DAY 9 EVERY 3 HOURS. DOSE RANGE WAS FROM 8-64 NG PER KILOGRAM. EMETINE DIHYDROCHLORIDE WAS USED.
Dose amountVAR
Number7
Percent yield49%
Qualitative resultACTIVE
AnimalMOUSE
Dose expressionDOSE
Expression resultILS