Experiment 606412

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

BRYOSTATIN 1

Details

PropertyValue
Pharmacology
PROTEIN KINASE C INHIBITION
OrganismEmpty organism
CitationSZALLASI,Z: DU,L: LEVINE,R: LEWIN,NE: NGUYEN,PN: WILLIAMS,MD: PETTIT,GR: BLUMBERG,PM:. (1996). THE BRYOSTATINS INHIBIT GROWTH OF B16/F10 MELANOMA CELLS IN VITRO THROUGH A PROTEIN KINASE C-INDEPENDENT MECHANISM: DISOCIATION OF ACTIVITIES USING 26-EPI-BRYOSTATIN 1.. 56(9)
Amount utilized
Compound isolated
DiseasePKC-ALPHA DOWN REGULATION, AFTER 24 HOURS.
Dose amount1.0 NANOMOLS
Number2
Qualitative resultACTIVE
Dose expressionED50