Experiment 611131
Worktypes
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | IV |
| Organism | Empty organism |
| Citation | SHENG,CY: GAO,WY: GUO,ZR: HE,LX:. (1997). ANISODAMINE RESTORES BOWEL CIRCULATION IN BURN SHOCK.. 23(2) |
| Amount utilized | |
| Compound isolated | |
| Disease | A CLINICAL STUDY WITH 6 BURN PATIENTS WITH A MEAN OF 65.3% TBSA BURN INJURY, AND 43.5% TBSA FULL-THICKNESS INJURY ASSESSED THE EFFECT OF ANISODAMINE ON RESTORING BOWEL CIRCULATION. GASTRIC PH RETURNED AND TNF WERE SIGNIFICANTLY LOWER 72 H AFTER TREATMENT AS COMPARED TO CONTROLS. CONCLUSION: ANISODAMINE MAY BE OF VALUE IN THE TREATMENT OF ENDOGENOUS ENDOTOXAEMIA SUBSEQUENT TO SPLANCHNIC VASOCONSTRICTION DUE TO HYPOVOLAEMIA. |
| Dose amount | 20.0 MG |
| Number | 1 |
| Qualitative result | ACTIVE |
| Animal | HUMAN ADULT |
| Dose expression | DOSE |
| Gender | MALE |