Experiment 622863

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

SHIKONIN,BETA-HYDROXY-ISO-VALERYL:

Alerts

SEE ARTICLE FOR OTHER TEST RESULTS.STATISTICAL DATA IN REPORT INDICATING SIGNIFICANT RESULTS.

Details

PropertyValue
Pharmacology
CYTOTOXIC ACTIVITY
OrganismEmpty organism
CitationHASHIMOTO,S: XU,M: MASUDA,Y: AIUCHI,T: NAJAJO,S: CAO,J: MIYAKOSHI,M: IDA,Y: NAKAYA,K:. (1999). BETA-HYDROXYISOVALERYLSHIKONIN INHIBITS THE CELL GROWTH OF VARIOUS CANCER CELL LINES AND INDUCES APOPTOSIS IN LEUKEMIA HL-60 CELLS THROUGH A MECHANISM DIFFERENT FROM THOSE OF FAS AND ETOPOSIDE.. 125(1)
Amount utilized
Compound isolated
DiseaseVS.VMRC-MELG.
Dose amount55.0 NANOMOLS
Number3
Qualitative resultWEAK ACTIVITY
AnimalCELL CULTURE
Dose expressionIC50