Experiment 631266
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | ORAL |
| Organism | Medicago sativa (FABACEAE) |
| Citation | DE LEO,V: LANZETTA,D: CAZZAVACCA,R: MORGANTE,G:. (1998). TREATMENT OF MENOPAUSAL SYMPTOMS WITH NON HORMONAL DRUG THERAPY.. 50() |
| Amount utilized | |
| Compound isolated | |
| Disease | USED IN COMBINATION WITH 120.0 MG SALVIA OFFICINALIS. HOT FLUSHES IN 30 MENOPAUSAL WOMEN WERE TREATED. HOT FLUSHES AND NIGHT SWEATING COMPLETELY DISAPPEARED IN 20 WOMEN, 4 WOMEN SHOWED GOOD IMPROVEMENT, AND THE OTHER 6 SHOWED A REDUCTION IN SYMPTOMS. GNRH AND TRH TESTS WERE PERFORMED IN 8 WOMEN TO EVALUATE TSH AND PRL RESPONSES BEFORE AND AFTER 3 MONTHS OF THERAPY. THE PLANTS INDUCED A SIGNIFICANT INCREASE IN PRL AND TSH RESPONSE TO TRH. BASAL LEVELS OF ESTRADIOL, LH, FSH, PRL AND TSH WERE UNCHANGED. |
| Dose amount | 60.0 MG |
| Number | 1 |
| Qualitative result | ACTIVE |
| Animal | HUMAN ADULT |
| Dose expression | DOSE |
| Extract | TYPE EXT NOT STATED |
| Gender | FEMALE |