| Disease | IN THIS RANDOMIZED, DOUBLE-MASKED STUDY, WE ASSESSED THE EFFECTS OF A GINKGO BILOBA(GB-8) EXTRACT ON ELDERLY VOLUNTEERS WITH AGE-RELATED COGNITIVE DYSFUNCTION. THE SUBJECTS WERE ALLOCATED TO ONE OF 3 GROUPS AND RECEIVED EITHER GB-8 40 MG OR 80
MG OR PLACEBO 3 TIMES DAILY FOR 3 MONTHS. BEFORE THERAPY WAS STARTED AND AFTER 1 AND 3 MONTHS OF TREATMENT, STANDARDIZED TESTING OF ATTENTION, CONCENTRATION, AND MEMORY WAS PERFORMED. THE SUBJECTS COMPLETED SELF-ASSESSMENTS BEFORE AND AFTER 3
MONTHS OF THERAPY, AND ARTERIAL BLOOD PRESSURE WAS MEASURED AT THE SAME INTERVALS. OBJECTIVE TEST RESULTS SHOWED THAT ATTENTION, CONCENTRATION, AND SHORT-TERM VERBAL MEMORY IMPROVED SIGNIFICANTLY IN SUBJECTS RECEIVING THE LOW-DOSE(STANDARD)
TREATMENT. SIMILAR IMPROVEMENTS WERE SEEN IN THE RESULTS OF THE SELF-ASSESSMENT TEST AND THE CLINICAL RATING. DIASTOLIC BLOOD PRESSURE DECREASED SIGNIFICANTLY DURING LOW-DOSE TREATMENT. TREATMENT WITH THE GB-8 EXTRACT WAS FOUND TO IMPROVE
OBJECTIVE MEASURES OF CEREBRAL FUNCTION IN ELDERLY SUBJECTS WITH MILD-TO-MODERATE COGNITIVE IMPAIRMENT; THE IMPROVEMENT APPEARED TO BE CLINICALLY RELEVANT. THE POSSIBLE ANTIHYPERTENSIVE ACTION OF GINKGO BILOBA EXTRACT IS SUFFICIENT TO WARRANT
FURTHER INVESTIGATION.
A COMMERCIAL PRODUCT, GB-8, WAS USED. |