Experiment 642396

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

BRYOSTATIN 1

Details

PropertyValue
Pharmacology
PROTEIN KINASE C INHIBITION
OrganismEmpty organism
CitationSPITALER,M: UTZ,I: HILBE,WG: HOFMANN,J: GRUNICKE,HH:. (1998). PKC-INDEPENDENT MODULAITON OF MULTIDRUG RESISTANCE IN CELLS WITH MUTANT (V185) BUT NOT WILD-TYPE (G185) P-GLYCOPROTEIN BY BRYOSTATIN 1.. 56(7)
Amount utilized
Compound isolated
DiseaseBINDS TO THE G185 AS WELL AS TO THE V185 FORM OF PGP.
Dose amount100.0 NANOMOLS
Number2
Qualitative resultACTIVE
AnimalCELL CULTURE
Dose expressionCONC USED