Experiment 644655
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | ORAL |
| Organism | Hypericum perforatum (CLUSIACEAE) |
| Citation | FIRENZUOLI,F: GORI,L:. (1999). IS THE ANTIDEPRESSANT EFFECT OF HYPERICUM EXTRACTS DEPENDING ON THEIR HYPERFORIN CONTENT?. 6(1) |
| Amount utilized | |
| Compound isolated | |
| Disease | IN A RANDOMIZED PLACEBO-CONTROLLED DOUBLE-BLIND TRIAL WITH 147 OUTPATIENTS SUFFERING FROM MILD TO MODERATELY SEVERE DEPRESSION WERE GIVEN 2 DIFFERENT EXTRACTS OF HYPERICUM PERFORATUM. AT THE END OF TREATMENT THE PATIENTS RECEIVING WS5572 SHOWED A STRONGER REDUCTION IN THE DEPRESSION SCALE(49%) AS COMPARED TO WS5573 GROUP(39%) AND 33% IN THE PLACEBO GROUP. A COMMERCIAL PRODUCT, WS 5572, WAS USED. |
| Dose amount | 900.0 MG |
| Number | 1 |
| Qualitative result | STRONG ACTIVITY |
| Animal | HUMAN ADULT |
| Per unit | DAY |
| Dose expression | DOSE |
| Extract | AERIAL PARTS |
| Gender | GIVEN TO BOTH SEXES |