Experiment 64646
Worktypes
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | ORAL |
| Organism | Empty organism |
| Citation | BKAHAT,MP: NANDI,N: PAI,HK: KHAN,BS:. (1974). THERAPEUTIC TRIAL OF BERBERINE SULPHATE IN NON-SPECIFIC GASTRO -ENTERITIS.. 68(2) |
| Amount utilized | |
| Compound isolated | |
| Disease | A CLINICAL TRIAL WAS USED FOR PATIENTS WITH ACUTE GASTRO-ENTERITIS TO STUDY THE EFFECT OF BERBERINE-SULPHATE. 30 PATIENTS WERE PLACED AT RANDOM IN 3 TREATMENT GROUPS. GROUP A WAS GIVEN BERBERAL-SULFATE . HALF OF THE DOSE IN CHILDREN AND 1/4 IN CHILDREN BELOW THE AGE OF 6 YEARS. GROUP B WAS GIVEN TETRACYCLIN. GROUP C OR CONTROL GROUP WAS TREATED WITH VIZ. MSIT BISMUTH ET KAOLIN AND NICOTINIC ACID 50 MG. STOOL EXAMINATION SHOWED EVIDENCE OF WORM INFEST ON 8 OUT OF 30 CASES. E.COLI WAS ISOLATED INPURE CUTLRUE IN 18 OUT OF 30 CASES. THE RESULTS SHOWED THAT BERBERINE SULPHATE IS REASONABLY EFFECTIVE IN CONTROLLIN GDIARRHEA IN HALF OF THE CASES, THOUGH IT'S ACTIONS ARE LESS SATISFACTORY THAN THAT OF TETRACYCLIN. |
| Number | 1 |
| Qualitative result | WEAK ACTIVITY |
| Animal | HUMAN ADULT |
| Dose expression | DOSE |
| Gender | GIVEN TO BOTH SEXES |