Experiment 64661
Worktypes
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | ORAL |
| Organism | Empty organism |
| Citation | WILKINSON,GR: BECKETT,AH:. (1968). ABSORPTION, METABOLISM, AND EXCRETION OF THE EPHEDRINES IN MAN. II.. 57(11) |
| Amount utilized | |
| Compound isolated | |
| Disease | THE KINETICS OF ABSORPTION, METABOLISM, AND EXCRETION OF NOREPHEDRINE, EPHEDRINE, AND METHYLEPHEDRINE, AFTER ORAL ANDMINISTRATION IN AQUEOUS SOLUTION, HAVE BEEN ELUCIDATED USING ANALOG COMPUTER ANALYSIS OF URINARY EXCRETION. RESULTS SHOWED THAT EPHEDRINE AND NOREPHEDRINE, WHEN PRESENT IN THE BODY AS METABOLITES, ARE ELIMINATED FASTER THAN WHEN THEY ARE ADMINISTERED PER SE. T1/2 FOR EPHEDRINE WAS 2.77, 2.52, 3.26 FOR THE 3 SUBJECTS. |
| Dose amount | VAR |
| Number | 3 |
| Qualitative result | ACTIVE |
| Animal | HUMAN ADULT |
| Dose expression | DOSE |
| Gender | MALE |