Experiment 647191

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

LAPACHONE,BETA:

Alerts

SEE ARTICLE FOR OTHER TEST RESULTS.

Details

PropertyValue
Pharmacology
TOPOISOMERASE I INHIBITION
OrganismEmpty organism
CitationWELLER,M: WINTER,S: SCHMIDT,C: ESSER,P: FONTANA,A: DICHGANS,J: GROSCURTH,P:. (1997). TOPOISOMERASE-I INHIBITORS FOR HUMAN MALIGNANT GLIOMA: DIFFERENTIAL MODULATION OF P53, P21, BAX AND BEL-2 EXPRESSION AND OF CD95-MEDIATED APOPTOSIS BY CAMPTOTHECIN AND BETA-LAPACHONE.. 73(5)
Amount utilized
Compound isolated
DiseaseVS.T98G CELLS GROWTH INHIBITION.
Dose amount1.0 MICROMOLS
Number4
Qualitative resultACTIVE
AnimalCELL CULTURE
Dose expressionIC50