Experiment 647236
Worktypes
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Organism | Empty organism |
| Citation | MIROSSAY,A: MIROSSAY,L: TOTHOVA,J: MISKOVSKY,P: ONDERKOVA,H: MOJZIS,J:. (1999). POTENTIATION OF HYPERICIN AND HYPOCRELLIN-INDUCED PHOTOTOXICITY BY OMEPRAZOLE.. 6(5) |
| Amount utilized | |
| Compound isolated | |
| Disease | LIGHT-INDUCED CYTOTOXICITY OF HYPERICIN AND HYPOCRELLIN AND POTENTIATING EFFECT OF OMEPRAZOLE ON HUMAN LEUKEMIC CELL LINE WAS STUDIED. RESULTS SHOW THAT EXCITED-STATE PROTON TRANSFER AND THE CONSEQUENT ACIDIFICATION OF HYPERICIN AND HYPOCRELLIN ENVIRONMENT COULD PLAY A ROLE IN THE BIOLOGICAL ACTIVITY OF BOTH AGENTS. |
| Dose amount | VAR |
| Number | 1 |
| Qualitative result | ACTIVE |
| Animal | CELL CULTURE |
| Dose expression | CONC USED |