Experiment 648093

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

TOPOSTATIN

Details

PropertyValue
Pharmacology
TOPOISOMERASE I INHIBITION
OrganismThermomonospora alba (THERMOMONOSPORACEAE)
CitationSUZUKI,K: YAMAIZUMI,M: TATEISHI,S: MONNAI,Y: UYEDA,M:. (1999). TOPOSTATIN, A NOVEL INHIBITOR OF TOPOISOMERASES I AND II PRODUCED BY THERMOMONOSPORA ALBA STRAIN NO.1520. III. INHIBITORY PROPERTIES.. 52(5)
Amount utilized
Compound isolated
DiseaseFROM CALF THYMUS GLAND.
Dose amount17.0 MICROMOLS
Number2
Qualitative resultACTIVE
AnimalCELL CULTURE
Dose expressionIC50