Experiment 653423
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | ORAL |
| Organism | Valeriana officinalis (VALERIANACEAE) |
| Citation | HOUGHTON,PJ:. (1999). THE SCIENTIFIC BASIS FOR THE REPUTED ACTIVITY OF VALERIAN.. 51(5) |
| Amount utilized | |
| Compound isolated | |
| Disease | A RANDOMIZED, DOUBLE-BLIND CONTROLLED STUDY ASSESSED THE EFFECTS OF VALERIAN. THE EXTRACTS PRODUCE SIGNIFICANT EFFECTS BUT THESE OFTEN TAKE AT LEAST 2 WEEKS TO BECOME APPARENT. IN CONTRAST TO MANY OTHER HYPNOTIC AGENTS. THERE IS LITTLE HANGOVER EFFECT AND THERE ARE ALSO NO OBVIOUS SIGNS OF INTERACTION WITH ALCOHOL. VALERIAN ADMINISTRATION IS ASSOCIATED WITH A REDUCTION IN REM SLEEP DURING THE FIRST PART OF THE NIGHT BUT AN INCREASE DURING THE LATTER STAGES. |
| Dose amount | VAR |
| Number | 3 |
| Qualitative result | ACTIVE |
| Animal | HUMAN ADULT |
| Dose expression | DOSE |
| Extract | ETOH(95%)EXT |
| Gender | GIVEN TO BOTH SEXES |