Experiment 654162

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

CURACIN A

Details

PropertyValue
Pharmacology
TUBULIN BINDING EFFECT
OrganismLyngbya majuscula (OSCILLATORIACEAE)
CitationVERDIER-PINARD,P: SITACHITTA,N: ROSSI,JV: SACKETT,DL: GERWICK,WH: HAMEL,E:. (1999). BIOSYNTHESIS OF RADIOLABELED CURACIN A AND ITS RAPID AND APPARENTLY IRREVERSIBLE BINDING TO THE COLCHICINE SITE OF TUBULIN.. 370(1)
Amount utilized
Compound isolated
DiseaseVS.PREINCUBATED WITH PODOPHYLLOTOXIN.
Dose amount10.0 MICROMOLS
Number4
Qualitative resultWEAK ACTIVITY
Dose expressionCONC USED