Experiment 657769

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

DOLASTATIN 10

Details

PropertyValue
Pharmacology
ANTIPROLIFERATION ACTIVITY
OrganismEmpty organism
CitationBAI,R: SCHWARTZ,RE: KEPLER,JA: PETTIT,GR: HAMEL,E:. (1996). CHARACTERIZATION OF THE INTERACTION OF CRYPTOPHYCIN 1 WITH TUBULIN: BINDING IN THE VINCA DOMAIN, COMPETITIVE INHIBITION OF DOLASTATIN 10 BINDING, AND AN UNUSUAL AGGREGATION REACTION.. 56(19)
Amount utilized
Compound isolated
Dose amount0.5 NANOMOLS
Number1
Qualitative resultACTIVE
AnimalCELL CULTURE
Dose expressionIC50