Experiment 657770

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

DOLASTATIN 10

Details

PropertyValue
Pharmacology
TUBULIN POLYMERIZATION INHIBITION
OrganismEmpty organism
CitationBAI,R: SCHWARTZ,RE: KEPLER,JA: PETTIT,GR: HAMEL,E:. (1996). CHARACTERIZATION OF THE INTERACTION OF CRYPTOPHYCIN 1 WITH TUBULIN: BINDING IN THE VINCA DOMAIN, COMPETITIVE INHIBITION OF DOLASTATIN 10 BINDING, AND AN UNUSUAL AGGREGATION REACTION.. 56(19)
Amount utilized
Compound isolated
Dose amount1.8 MICROMOLS
Number2
Qualitative resultACTIVE
Dose expressionIC50