Experiment 657827

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

PINORESINOL,(+):

Details

PropertyValue
Pharmacology
TUMOR NECROSING FACTOR SYNTHESIS INHIBITION
OrganismCoptis japonica (RANUNCULACEAE)
CitationCHO,JY: PARK,J: YOO,ES: YOSHIKAWA,K: BAIK,KU: LEE,JS: PARK,MH:. (1998). INHIBITORY EFFECT OF LIGNANS FROM THE RHIZOMES OF COPTIS JAPONICA VAR. DISSECTA ON TUMOR NECROSIS FACTOR-ALPHA PRODUCTION IN LIPOPOLYCHARIDE-STIMULATED RAW264.7 CELLS.. 21(1)
Amount utilized
Compound isolated
DiseaseVS.LPS-STIMULATED RAW264.7 CELLS.
Dose amount69.8 MICROMOLS
Number6
Qualitative resultACTIVE
AnimalCELL CULTURE
Dose expressionIC50