Experiment 661245

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

CAMPTOTHECIN

Alerts

SEE ARTICLE FOR OTHER TEST RESULTS.

Details

PropertyValue
Pharmacology
TOPOISOMERASE I INHIBITION
OrganismEmpty organism
CitationHOLDEN,JA: WALL,ME: WANI,MC: MANIKUMAR,G:. (1999). HUMAN DNA TOPOISOMERASE I: QUANTITATIVE ANALYSIS OF THE EFFECTS OF CAMPTOTHECIN ANALOGS AND THE BENZOPHENANTHRIDINE ALKALOIDS NITIDINE AND 6-ETHOXYDIHYDRONITIDINE ON DNA TOPOISOMERASE I-INDUCED DNA STRAND BREAKAGE.. 370(1)
Amount utilized
Compound isolated
Dose amount1.0 MICROMOLS
Number2
Qualitative resultACTIVE
Dose expressionIC50