Experiment 667529

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

CORREOLIDE

Details

PropertyValue
Pharmacology
CALCIUM LEVEL DECREASE(INTRACELLULAR)
OrganismEmpty organism
CitationKOO,GC: BLAKE,JT: SHAH,K: STARUCH,MJ: DUMONT,F: WUNDERLER,D: SANCHEZ,M: MC MANUS,OB: SIROTINA-MEISHER,A: FISCHER,P: BOLTZ,RC: GOETZ,MA: BAKER,R: BAO JM: KAYSER,F: RUPPRECHT,KM: PARSONS,WH: TONG,XC: ITA,IE: PIVNICHNY,J: VINCENT,S: CUNNINGHAM,P: HORA JR,D: FEENEY,W: KACZOROWSKI,G: SPRINGER,MS:. (1999). CORREOLIDE AND DERIVATIVES ARE NOVEL IMMUNOSUPPRESSANTS BLOCKING THE LYMPHOCYTE KV1.3 POTASSIUM CHANNELS.. 197(2)
Amount utilized
Compound isolated
DiseaseVS.ANTI-CD3 INDUCED RISE IN CA2+.
Dose amount10.0 MICROMOLS
Number6
Qualitative resultACTIVE
AnimalCELL CULTURE
Dose expressionCONC USED