| Disease | TO STUDY THE EFFECTS OF GINKGO BILOBA EXTRACT 761 FROM THE POINTS OF VIEW OF HEMORRHEOLOGY FOR PATIENTS OF PERIPHERAL ARTERIAL OCCLUSIVE DISEASE (PAOD). THE TREATMENT WITH GB3 (240 MG.D-1) AND PAIN-FREE WALKING DISTANCE (PFWD) WERE CARRIED OUT
24 PAOD PATIENTS (12 NONDIABETIC, ND AND 12 DIABETIC, D) OVER 48 WK. THE PARAMETERS ERYTHROCYTES STIFFNESS (ES) AND RELAXATION TIME (RT), THE BLOOD PLASMA VISCOSITY (NETA), THE PLASMA FIBRINOGEN CONCENTRATION (CF) AND THE BLOOD SEDIMENTATION
RATE (BSR), THE PFWD, AND MAXIMAL WALKING DISTANCE (MWD) WERE DETERMINED. THROUGHOUT 11 WK OF TREATMENT ES, RT, NETA, AND CF DECREASED GRADUALLY AND PFWD IMPROVED. BETWEEN 16 AND 48 WK, ES, AND RT WERE NO LONGER SIGNIFICANTLY DIFFERENT FROM
THE CONTROLS, WHEREAS NETA AND CF DECREASED GRADUALLY BUT REMAINED HIGHER THAN NORMAL, BSR DECREASED, AND THE PFWD IMPROVED BY A FACTOR OF 3.8 TIMES (D) AND 3.3 TIMES (ND).
A COMMERCIAL PRODUCT, EGB-761, WAS USED. |