Experiment 67007
Worktypes
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | ORAL |
| Organism | Commiphora mukul (BURSERACEAE) |
| Citation | KUPPURAJAN,K: RAJAGOPALAN,SS: RAO,TK: SITARAMAN,R:. (1978). EFFECT OF GUGGULU (COMMIPHORA MUKUL-ENGL.) ON SERUM LIPIDS IN OBESE, HYPERCHOLESTEROLEMIC AND HYPERLIPEMIC CASES.. 26(5) |
| Amount utilized | |
| Compound isolated | |
| Disease | A CONTROLLED CLINICAL TRIAL TO STUDY THE EFFECT OF THE GUM OF COMMIPHORA MUKUL ENGL.(GUM GUGGULU) AND FRACTION 'A' OF THE PETROLEUM ETHER EXTRACT OF GUGGULU ON SERUM LIPIDS OF 120 OBESE, HYPERCHOLESTEROLEMIC AND HYPERLIPEMIC CASES WAS CONDUCTED. FRACTION 'A' OF THE PETROLEUM ETHER EXTRACT OF GUGGULU WAS SHOWN TO BRING ABOUT A SIGNIFICANT REDUCTION IN SERUM CHOLESTEROL AND SERUM TOTAL LIPIDS OVER A TREATMENT PERIOD OF 21 DAYS AND THE RESULTS COMPARE FAVOURABLY WITH THE EFFECT OF CLOFIBRATE (ATROMID-S) ON SERUM LIPIDS. DECOCTION CONTAINED GUM GUGGULU, TERMINALIA CHEBULA, TERMINALIA BELERICA AND EMBLICA OFFICINALIS. |
| Dose amount | 6.0 GM |
| Number | 2 |
| Qualitative result | ACTIVE |
| Animal | HUMAN ADULT |
| Per unit | DAY |
| Dose expression | DOSE |
| Extract | DECOCTION |
| Gender | GIVEN TO BOTH SEXES |