Experiment 670685
Worktypes
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Organism | Empty organism |
| Citation | MOORE,LB: GOODWIN,B: JONES,SA: WISELY,GB: SERABJIT-SINGH,CJ: WILLSON,TM: COLLINS,JL: KLIEWER,SA:. (2000). ST. JOHN'S WORT INDUCES HEPATIC DRUG METABOLISM THROUGH ACTIVATION OF THE PREGNANE X RECEPTOR.. 97(13) |
| Amount utilized | |
| Compound isolated | |
| Disease | INDUCED ACTIVATION OF THE PREGNANE X RECEPTOR THAT REGULATES THE EXPRESSION OF CYTOCHROME P450 3A4 MONOOXYGENASE. |
| Dose amount | 10.0 MICROMOLS |
| Number | 4 |
| Qualitative result | WEAK ACTIVITY |
| Animal | HUMAN ADULT |
| Dose expression | CONC USED |