Experiment 67072
Worktypes
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | ORAL |
| Organism | Commiphora mukul (BURSERACEAE) |
| Citation | SINGH,RB: NIAZ,MA: GHOSH,S:. (1994). HYPOLIPIDEMIC AND ANTIOXIDANT EFFECTS OF COMMIPHORA MUKUL AS AN ADJUNCT TO DIETARY THERAPY IN PATIENTS WITH HYPERCHOLESTEROLEMIA.. 8(4) |
| Amount utilized | |
| Compound isolated | |
| Disease | THE EFFECTS OF THE ADMINISTRATION OF 50 MG OF GUGGULIPID OR PLACEBO CAPSULES TWICE DAILY FOR 24 WEEKS WERE COMPARED AS ADJUNCTS TO A FRUIT- AND VEGETABLE-ENRICHED PRUDENT DIET IN THE MANAGEMENT OF 61 PATIENTS WITH HYPERCHOLESTEROLEMIA (31 IN THE GUGGULIPID GROUP AND 30 IN THE PLACEBO GROUP) IN A RANDOMIZED, DOUBLE-BLIND FASHION. GUGGULIPID DECREASED THE TOTAL CHOLESTEROL LEVEL BY 11.7%, THE LOW DENSITY LIPOPROTEIN CHOLESTEROL(LDL) BY 12.5%, TRIGLYCERIDES BY 12.0%, AND THE TOTAL CHOLESTEROL/HIGH DENSITY LIPOPROTEIN (HDL) CHOLESTEROL RATIO BY 11.0% FROM THE POSTDIET LEVELS, WHEREAS THELEVELS WERE UNCHANGED IN THE PLACEBO GROUP. |
| Dose amount | 100.0 MG |
| Number | 2 |
| Qualitative result | ACTIVE |
| Animal | HUMAN ADULT |
| Per unit | DAY |
| Dose expression | DOSE |
| Extract | PET ETHER EXT |
| Gender | GIVEN TO BOTH SEXES |