Experiment 67310
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | ORAL |
| Organism | Urtica dioica (URTICACEAE) |
| Citation | SOKELAND,J:. (2000). COMBINED SABAL AND URTICA EXTRACT COMPARED WITH FINASTERIDE IN MEN WITH BENIGN PROSTATIC HYPERPLASIA: ANALYSIS OF PROSTATE VOLUME AND THERAPEUTIC OUTCOME.. 86(4) |
| Amount utilized | |
| Compound isolated | |
| Disease | A SUBGROUP OF 431 PATIENTS WAS ANALYSED FROM A RANDOMIZED, MULTICENTRE, DOUBLE-BLIND CLINICAL TRIAL INVOLVING 543 PATIENTS WITH THE EARLY STAGES OF BPH. PATIENTS RECEIVED A FIXED COMBINATION OF EXTRACTS OF SAW PALMETTO FRUIT (SERENOA REPENS) AND NETTLE ROOT (URTICA DIOICA) (PRO 160/120) OR THE SYNTHETIC 5-ALPHA-REDUCTASE INHIBITOR FINASTERIDE. THE PATIENTS ASSESSED HAD VALID ULTRASONOGRAPHIC MEASUREMENTS AND BASELINE PROSTATE VOLUMES OF EITHER <40 ML OR >40 ML. THE MEAN MAXIMUM URINARY FLOW INCREASED (FROM BASELINE VALUES) AFTER 24 WEEKS BY 1.9 ML/S WITH PRO 160/120 AND BY 2.4 ML/S WITH FINASTERIDE. THE PRESENT ANALYSIS SHOWED THAT THE EFFICACY OF BOTH PRO 160/120 AND FINASTERIDE WAS EQUIVALENT. |
| Dose amount | 240.0 MG |
| Number | 1 |
| Qualitative result | ACTIVE |
| Animal | HUMAN ADULT |
| Per unit | DAY |
| Dose expression | DOSE |
| Extract | HYDRO-ALCOHOLIC EXT |
| Gender | MALE |