Experiment 674321

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

PARTHENOLIDE

Details

PropertyValue
Pharmacology
NITRIC OXIDE SYNTHASE INHIBITION
OrganismEmpty organism
CitationFUKUDA,K: HIBIYA,Y: MUTOH,M: OHNO,Y: YAMASHITA,K: AKAO,S: FUJIWARA,H:. (2000). INHIBITION BY PARTHENOLIDE OF PHORBOL ESTER-INDUCED TRANSCRIPTIONAL ACTIVATION OF INDUCIBLE NITRIC OXIDE SYNTHASE GENE IN A HUMAN MONOCYTE CELL LINE THP-1.. 60(4)
Amount utilized
Compound isolated
DiseaseVS.TPA-INDUCED INCREASE IN INOS PROMOTER ACTIVITY.
Dose amount2.0 MICROMOLS
Number2
Qualitative resultACTIVE
AnimalCELL CULTURE
Dose expressionIC50