Experiment 676211
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | ORAL |
| Organism | Camellia sinensis (THEACEAE) |
| Citation | BROWN,MD:. (1999). GREEN TEA (CAMELLIA SINENSIS) EXTRACT AND ITS POSSIBLE ROLE IN THE PREVENTION OF CANCER.. 4(5) |
| Amount utilized | |
| Compound isolated | |
| Disease | THE ASSOCIATION BETWEEN CONSUMPTION OF GREEN TEA PRIOR TO CLINICAL CANCER ONSET AND VARIUS CLINICAL PARAMETERS WAS ASSESSED AMONG 472 PATIENTS WITH STAGE I, II, AND III BREAST CANCER. INCREASED CONSUMPTION OF GREEN TEA WAS CLOSELY ASSOCIATED WITH A DECREASED NUMBER OF AXILLARY LYMPH NODE METASTASES, ESPECIALLY AMONG PREMENOPAUSAL PATINENTS WITH STAGE I AND STAGE II BREAST CANCERS. IN A SEVEN-YEAR FOLLOW-UP STUDY OF THESE PATIENTS, INCREASED COSNUMPTION OF GREEN TEA CORRELATED WITH A DECREASED RECURRENCE OF STAGE I AND II BREAST CANCER (P<0.05 FOR CRUDE DISEASE-FREE SURVIVAL); THE RECURRENCE RATE WAS 16.7 PERCENT AMONG THOSE CONSUMING AND 24.3 PER DAY, AND THE RELATIVE RISK OF OCCURRENCE WAS 0.564 (95% CI, 0.350-0.911) AFTER ADJUSTMENT FOR OTHER LIFESTYLE FACTORS. HOWEVER, NO IMPROVEMENT IN PROGNOSIS WAS OBSERVED IN STAGE III BREAST CANCER. |
| Number | 10 |
| Qualitative result | ACTIVE |
| Animal | HUMAN ADULT |
| Dose expression | DOSE |
| Extract | INFUSION |
| Gender | FEMALE |