Experiment 67657
Worktypes
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | ORAL |
| Organism | Trigonella foenum-graecum (FABACEAE) |
| Citation | LAMBERT,JP: CORMIER,J:. (2001). POTENTIAL INTERACTION BETWEEN WARFARIN AND BOLDO-FENUGREEK.. 21(4) |
| Amount utilized | |
| Compound isolated | |
| Disease | A PATIENT WAS TREATED WITH WARFARIN FOR ATRIAL FIBRILLATION. DURING TREATMENT, AN INCREASE IN INTERNATIONAL NORMALIZED RATIO (INR) AND HER ADMISSION THAT SHE WAS TAKING A VARIETY OF NATURAL PRODUCTS, TO INCLUDE BOLDO AND FENUGREEK, LED US TO SUSPECT THAT SOME OF THESE NATURAL PRODUCTS COULD ALTER THE EFFECT OF WARFARIN. WHEN SHE STOPPED THE CULPABLE PRODUCTS, THE INR RETURNED TO NORMAL AFTER 1 WEEK. |
| Number | 1 |
| Qualitative result | ACTIVE |
| Animal | HUMAN ADULT |
| Dose expression | DOSE |
| Extract | SEEDS |
| Gender | FEMALE |