Experiment 67666
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | ORAL |
| Organism | Empty organism |
| Citation | DALV,PA: KRIEGER,DR: DULLOO,AG: YOUNG,JB: LANDSBERG,L:. (1993). SAFETY AND EFFICACY FOR TREATMENT OF HUMAN OBESITY.. 17(1) |
| Amount utilized | |
| Compound isolated | |
| Disease | THE SAFETY AND EFFICACY OF A MIXTURE OF EPHEDRINE (75-150MG), CAFFEINE (150MG) AND ASPIRIN (330MG), IN DIVIDED PREMEAL DOSES, WERE INVESTIGATED IN 24 OBESE HUMANS IN A RANDOMIZED DOUBLE BLIND PLACEBO CONTROLLED TRIAL. OVERALL WEIGHT LOSS OVER 8 WEEKS WAS 2.2KG FOR ECA VS. 0.7KG FOR PLACEBO 8 OF 13 PLACEBO SUBJECTS RETURNED 5 MONTHS LATER AND RECEIVED ECA IN AN UNBLINDED CROSSOVER. AFTER 8 WEEKS, MEAN WEIGHT LOSS WITH ECA WAS 3.2KG VS 1.3KG FOR PLACEBO. |
| Dose amount | 150.0 MG |
| Number | 2 |
| Qualitative result | ACTIVE |
| Animal | HUMAN ADULT |
| Per unit | DAY |
| Dose expression | DOSE |
| Gender | GIVEN TO BOTH SEXES |