Experiment 67754
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | ORAL |
| Organism | Clinacanthus siamensis (ACANTHACEAE) |
| Citation | VONGSAKUL,TP: KETSA ARD,K:. (1995). IMMUNOSTIMULATORY EFFECT OF A THAI FOLKLORIC REMEDY IN BREAST CANCER PATIENTS.. 2(1) |
| Amount utilized | |
| Compound isolated | |
| Disease | THE EFFECT OF TREATMENT WITH AN EXTRACT OF THIS REMEDY ON THE EFFECTOR CELLS INVOLVED IN CANCER IMMUNITY, NATURAL KILLER (NK) CELLS AND MONOCYTE/MACROPHAGES, WAS STUDIED IN 13 BREAST CANCER PATIENTS. TREATMENT OF THE PATIENTS WITH THE EXTRACT FOR 2 WEEKS SIGNIFICANTLY INCREASED IN VITRO NK CELL CYTOTOXIC ACTIVITY AGAINST K562 ERYTHROLEUKEMIC CELLS. IT ALSO INCREASED THE RELEASE OF TUMOR NECROSIS FACTOR-ALPHA FROM MONOCYTE/MACROPHAGES. THE ADDITION OF CHEMOTHERAPEUTIC DRUGS TO THE TREATMENT SCHEDULE SEEMED TO DECREASE THESE EFFECTOR CELL FUNCTIONS. TREATMENT WITH THE EXTRACT OF THIS THAI FOLKLORIC REMEDY MAY BE A USEFUL ADDITION TO CURRENT THERAPIES FOR BREAST CANCER. |
| Dose amount | 0.50 L |
| Number | 1 |
| Qualitative result | ACTIVE |
| Animal | HUMAN ADULT |
| Per unit | DAY |
| Dose expression | DOSE |
| Extract | DECOCTION |
| Gender | FEMALE |